- Helpline Number
Dial 1800 419 9801
(From 9a.m. to 9p.m.)
- State-of-the-art diagnosis
- Enquiry / Appointment
- South Kolkata Unit
Flat no 101, 1st Floor,
28A, Dr. Sarat Banerjee Road,
Kolkata 700 029
North Kolkata Unit P - 30, VIP Complex Kankurgachi
CIT Road ,
Kolkata - 700054
Screening for Chromosomal problems/ Downs Syndrome
First Trimester Screening (The 11-13 weeks scan)
This scan is carried out from 11 weeks to 13 weeks and 6 days. The scan is usually performed transabdominally.
- To assess the risks of Down’s syndrome and other chromosomal abnormalities.Each woman will be given an estimate of her individual risk for this pregnancy. This is calculated by taking into account the age and weight of the mother along with certain demographic I clinical variables, measurement of two pregnancy hormones in the mothers blood (Free beta hcg & PAPA) and the scan findings of thickness of skin at the back of baby’s neck (nuchaltranslucency) with presence or absence of nasal bone.
- To date the pregnancy accurately.
- To assess a multiple pregnancy (Approximately 2% of natural and 10% of assisted conceptions) to determine ifthe babies share the same placenta which can lead to problems in the pregnancy. In such cases it would be advisable to monitor the pregnancy more closely.
- To diagnose certain major physical abnormalities of baby which may be visible at this stage.
- Based on the calculation, the test will be reported as either Negative Screening (Normal result) or Positive Screening (Abnormal result). Parents will receive full counselling concerning the significance of the positive test and the various options for further testing .Only you can then decide if you wish to have an invasive diagnostic test for final confirmation of any problem in baby.
- If the test is reported as normal, it is recommended that you have an Anomaly Scan at 20 weeks to check for physical abnormalities in the baby.
The Preparation and After
- You may eat normally before.
- We will need a reasonably full bladder for the test so that you need to drink sufficient water for about an hour before the test and hold your urine.
- After the sonography is done, you will be taken for a blood sample collection in the normal way after which you may leave. Result should be available in about 5 working days.
Second Trimester Screening (Quadruple Test)
- The Objective of Second Trimester Screening is similar to First Trimester Screening, except the fact that it is offered to women who are seen later in pregnancy after 16 weeks upto 21 weeks. Here also ultrasonographic parameters of the fetus are combined with four pregnancy hormones and Demographic variables to calculate the result. Similarly, it is reported as positive Screening (Abnormal Result) or Negative Screening (Normal Result). In case of positive screening, further invasive testing (amniocentesis or CVS) is offered as Diagnostic or confirmatory test for Downs Syndrome. Quadruple Test can also indicate fora possible presence of defect in spinal cord (Spina Bifida).
- Preparation and procedure is similar to First Trimester Screening, except requirement of a full bladder is not essential. Report is available usually in a week after the test.